{"id":2664,"date":"2025-01-29T01:33:26","date_gmt":"2025-01-29T01:33:26","guid":{"rendered":"https:\/\/site.itshrt.com\/worldnews\/state-department-permits-distribution-of-h-i-v-medications-to-resume-for-now\/"},"modified":"2025-01-29T01:33:26","modified_gmt":"2025-01-29T01:33:26","slug":"state-department-permits-distribution-of-h-i-v-medications-to-resume-for-now","status":"publish","type":"post","link":"https:\/\/site.itshrt.com\/worldnews\/state-department-permits-distribution-of-h-i-v-medications-to-resume-for-now\/","title":{"rendered":"State Department Permits Distribution of H.I.V. Medications to Resume \u2014 for Now"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6606220950177433\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<!-- ItShrt World News -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-6606220950177433\"\r\n     data-ad-slot=\"1882483372\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\r\n<br \/>\n<\/p>\n<div data-testid=\"companionColumn-0\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">The Trump administration on Tuesday issued a waiver for lifesaving medicines and medical services, offering a reprieve for a worldwide H.I.V. treatment program that was halted last week.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The waiver, announced by Secretary of State Marco Rubio, seemed to allow for the distribution of H.I.V. medications, but whether the waiver extended to preventive drugs or other services offered by the program, the President\u2019s Emergency Plan for AIDS Relief, was not immediately clear.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Still, PEPFAR\u2019s future remains in jeopardy, with potential consequences for more than 20 million people \u2014 including 500,000 children \u2014 who could lose access to lifesaving medications. Without treatment, millions of people with H.I.V. in low-income countries would be at risk of full-blown AIDS and of premature death.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cWe can very rapidly return to where the pandemic is exploding, like it was back in the 1980s,\u201d said Dr. Steve Deeks, an H.I.V. expert at the University of California, San Francisco.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-1\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cThis really cannot happen,\u201d he said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">On Monday, the Trump administration ordered health organizations in other countries to immediately stop distributing H.I.V. medications purchased with U.S. aid. The directive stemmed from a freeze \u2014 which may become permanent \u2014 in the activities of PEPFAR, a $7.5 billion program overseen by the State Department.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Since it started in 2003, PEPFAR is estimated to have saved more than 25 million lives; more than 5.5 million children have been born free of H.I.V. who otherwise would have been infected.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">In South Africa alone, PEPFAR\u2019s shutdown would add more than a half million new H.I.V. infections and more than 600,000 related deaths over the next decade, according to one estimate.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The organization employs 270,000 doctors, nurses, pharmacists and other health workers. They had been told not to report to work or to serve patients.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-2\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">PEPFAR\u2019s end would \u201ccreate instability and potentially collapse several countries\u2019s AIDS programs that will be difficult to repair, if and when PEPFAR funding becomes available again,\u201d said Dr. Salim Abdool Karim, an infectious disease epidemiologist at the University of KwaZulu-Natal in Durban, South Africa.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-3\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Dr. Abdool Karim said countries should stop relying on PEPFAR and support their own citizens, a goal that the program\u2019s staff and partners had been working toward. But ideally that shift would happen gradually, over years during which PEPFAR would train local health workers and prepare them for the transition, he said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThis is not a bad opportunity for countries to take greater responsibility,\u201d he said. \u201cBut I think they can\u2019t do it if it\u2019s done in this kind of haphazard and unplanned way.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Here\u2019s what he and others expect from PEPFAR\u2019s unexpected pause.<\/p>\n<h2 class=\"css-13o6u42 eoo0vm40\" id=\"link-70d7c392\">Sudden stops to H.I.V. treatment can quickly turn dangerous.<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">Every day, more than 220,000 people pick up H.I.V. medications at clinics funded by PEPFAR; the number included more than 7,400 children under 15, according to data published on Tuesday by AMFAR, The Foundation for AIDS Research.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The drugs work by suppressing H.I.V. in the body. When patients go off the drugs, the virus grabs the opportunity to rebound \u2014 and quickly. Within a week, H.I.V. levels will skyrocket from undetectable levels to more than 100,000 copies per milliliter of blood.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-4\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cThat may be a time where you are very much at risk of passing the virus on to others,\u201d Dr. Sallie Permar, a pediatrician and H.I.V. expert at Weill Cornell Medicine, said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Then, the virus will start attacking a certain type of immune cell, crippling the body\u2019s ability to fend off other infections, including tuberculosis, which frequently accompanies H.I.V. infection.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Spiking H.I.V. levels at first may cause flulike symptoms, including sore throat, swollen glands and fatigue. The immune system will likely marshal enough force to suppress the virus temporarily, but H.I.V. is adept at hiding until it finds the right opportunity to re-emerge.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">When that occasion arises, \u201cthey can develop AIDS and progress,\u201d Dr. Deeks said.<\/p>\n<h2 class=\"css-13o6u42 eoo0vm40\" id=\"link-1a792cad\">Children may be among the hardest hit.<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">PEPFAR is best known for financing H.I.V. treatment programs, but its funds also go to drugs for prevention, outreach and testing, and to support for orphans and women experiencing gender-based violence.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The loss of resources for each of these efforts will derail the fight against AIDS, said Dr. Glenda Gray, a pediatric H.I.V. expert at Wits University in South Africa.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-5\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cIf H.I.V. testing falls by the wayside, it\u2019s unlikely that we will be able to even diagnose people who need to go into treatment,\u201d she said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">If a pregnant or breastfeeding woman has H.IV. but is not tested and not treated, she may pass the virus to her child. The higher her viral load, the more likely this is to occur.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Children with H.I.V. are less likely to be diagnosed than adults, and may not be treated till the virus makes them visibly very sick. This progression can be much more rapid in children than in adults, Dr. Gray said, \u201cand obviously, children who are untreated are likely to die.\u201d<\/p>\n<h2 class=\"css-13o6u42 eoo0vm40\" id=\"link-7eead73a\">Inconsistent treatment drives drug resistance.<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">As people lose access to medications, they may try to spread out their supplies by alternating days or to share their pills with others. If the virus replicates in people with only partial protection, it can learn to evade those defenses and become resistant to the medications.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">People living with the virus may then pass the resistant virus on to others.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThat becomes a big problem, because now, suddenly, our cheap first-line drugs might not work when we have to restart them on treatment,\u201d Dr. Abdool Karim said.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-6\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">A virus that is resistant to treatments will also be better at evading vaccine candidates being tested.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cNot only are we looking at more drug resistance, but we\u2019re looking at losing whatever ability we had to make an effective vaccine,\u201d Dr. Permar said.<\/p>\n<h2 class=\"css-13o6u42 eoo0vm40\" id=\"link-39cc6247\">PEPFAR\u2019s end may affect Americans, too.<\/h2>\n<p class=\"css-at9mc1 evys1bk0\">More than one million Americans are living with the virus, and more than 30,000 become infected each year. If H.I.V. becomes resistant to available medications, it isn\u2019t likely to remain in low-income countries. Americans, too, will be at risk.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">They may also face indirect harms from ending PEPFAR. Creating huge populations of immunocompromised people may mean that other pathogens have an opportunity to spread. For example, dangerous Covid variants, including Omicron, are thought to have evolved in immunocompromised people with H.I.V.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">At the same time, people worldwide have benefited from trials conducted under PEPFAR\u2019s auspices, showing the importance of treating H.I.V. early, demonstrating that pregnant women can safely breastfeed as long as they are treated and that H.I.V. infections can be prevented with long-acting drugs.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-7\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cAmerica has gotten an amazing amount of love around the world because of what it\u2019s done,\u201d Dr. Deeks said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cFrom a humanitarian perspective, I can\u2019t imagine anyone really wants to go along this pathway,\u201d he added. \u201cThis doesn\u2019t make any sense on any level.\u201d<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6606220950177433\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<!-- ItShrt World News -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-6606220950177433\"\r\n     data-ad-slot=\"1882483372\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.nytimes.com\/2025\/01\/28\/health\/trump-pepfar-freeze.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Trump administration on Tuesday issued a waiver for lifesaving medicines and medical services, offering a reprieve for a worldwide<\/p>\n","protected":false},"author":1,"featured_media":2665,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[984,785,622,407,551,713,447,626,630,188],"class_list":["post-2664","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-2","tag-africa","tag-developing-countries","tag-disease-rates","tag-foreign-aid","tag-medicine-and-health","tag-presidents-emergency-plan-for-aids-relief","tag-south-africa","tag-tests-medical","tag-viruses","tag-your-feed-science"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>State Department Permits Distribution of H.I.V. 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