{"id":18789,"date":"2025-04-11T16:08:51","date_gmt":"2025-04-11T16:08:51","guid":{"rendered":"https:\/\/site.itshrt.com\/worldnews\/pig-kidney-removed-from-alabama-woman-after-organ-rejection\/"},"modified":"2025-04-11T16:08:51","modified_gmt":"2025-04-11T16:08:51","slug":"pig-kidney-removed-from-alabama-woman-after-organ-rejection","status":"publish","type":"post","link":"https:\/\/site.itshrt.com\/worldnews\/pig-kidney-removed-from-alabama-woman-after-organ-rejection\/","title":{"rendered":"Pig Kidney Removed From Alabama Woman After Organ Rejection"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6606220950177433\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<!-- ItShrt World News -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-6606220950177433\"\r\n     data-ad-slot=\"1882483372\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\r\n<br \/>\n<\/p>\n<div data-testid=\"companionColumn-0\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Surgeons removed a genetically engineered pig\u2019s kidney from an Alabama woman after she experienced acute organ rejection, NYU Langone Health officials said on Friday.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Towana Looney, 53, lived with the kidney for 130 days, which is longer than anyone else has tolerated an organ from a genetically modified animal. She has resumed dialysis, hospital officials said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Dr. Robert Montgomery, Ms. Looney\u2019s surgeon and the director of the NYU Langone Transplant Institute, said that the so-called explant was not a setback for the field of xenotransplantation \u2014 the effort to use organs from animals to replace those that have failed in humans.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThis is the longest one of these organs has lasted,\u201d he said in an interview, adding that Ms. Looney had other medical conditions that might have complicated her prognosis.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-1\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cAll this takes time,\u201d he said. \u201cThis game is going to be won by incremental improvements, singles and doubles, not trying to swing for the fences and get a home run.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Further treatment of Ms. Looney might have salvaged the organ, but she and her medical team decided against it, Dr. Montgomery said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cNo. 1 is safety \u2014 we needed to be sure that she was going to be OK,\u201d he said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Another patient, Tim Andrews of Concord, N.H., has been living with a kidney from a genetically modified pig since Jan. 25. He has been hospitalized twice for biopsies, doctors at Massachusetts General Hospital in Boston said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Two other patients who received similar kidneys in recent years died, as did two patients given hearts from genetically modified pigs.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Ms. Looney, who has returned to her home in Alabama after coming to New York for treatment and was not available for comment, said in a statement that she was grateful for the opportunity to participate in the groundbreaking procedure.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-2\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">\u201cFor the first time since 2016, I enjoyed time with friends and family without planning around dialysis treatments,\u201d Ms. Looney said in a statement provided by NYU Langone.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThough the outcome is not what anyone wanted, I know a lot was learned from my 130 days with a pig kidney \u2014 and that this can help and inspire many others in their journey to overcome kidney disease,\u201d she said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Hospital officials said that Ms. Looney\u2019s kidney function dropped after she experienced rejection of the organ. The cause was being investigated, Dr. Montgomery said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But the response followed a reduction in immunosuppressive medications she had been taking, done in order to treat an unrelated infection, he added.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The first sign of trouble was a blood test done in Alabama that showed Ms. Looney had elevated levels of creatinine, a waste product that is removed from the blood through the kidneys. Elevated levels signal there may be a problem with kidney function.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-3\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Ms. Looney was admitted to the hospital, but when her creatinine levels continued to climb, she flew to New York, where doctors biopsied the kidney and found clear signs of rejection, Dr. Montgomery said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The kidney was removed last Friday, hospital officials said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201dThe decision was made by Ms. Looney and her doctors that the safest intervention would be to remove the kidney and return to dialysis rather than giving additional immunosuppression,\u201d Dr. Montgomery said in a statement.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">United Therapeutics Corporation, the biotech company that produced the pig that provided Ms. Looney\u2019s kidney, thanked her for her bravery and said that the organ appeared to function well until the rejection.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The company expects to start a clinical trial of pig-kidney transplantation this year, starting with six patients and eventually growing to 50 patients.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Pig organs are seen as a potential solution to the shortage of donated organs, especially kidneys. More than 550,000 Americans have kidney failure and require dialysis, and about 100,000 of them are on a waiting list to receive a kidney.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But there is an acute need for human organs, and fewer than 25,000 transplants were performed in 2023. Many patients die while waiting.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6606220950177433\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<!-- ItShrt World News -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-6606220950177433\"\r\n     data-ad-slot=\"1882483372\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.nytimes.com\/2025\/04\/11\/health\/pig-kidney-transplant-looney.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Surgeons removed a genetically engineered pig\u2019s kidney from an Alabama woman after she experienced acute organ rejection, NYU Langone Health<\/p>\n","protected":false},"author":1,"featured_media":18790,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[5878,1920,1917,2509,3917,1919,5879,1918,188],"class_list":["post-18789","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-dialysis","tag-genetic-engineering","tag-kidneys","tag-new-york-university-langone-health","tag-organ-donation","tag-pigs","tag-towana-looney","tag-transplants","tag-your-feed-science"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pig Kidney Removed From Alabama Woman After Organ Rejection - World News<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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